Oral Bioavailability Assessment. Basics and Strategies for Drug Discovery and Development; John Wiley & Sons Limited
14442 р.
- Издатель: John Wiley & Sons Limited
- ISBN: 9781118916940
- Книги: Медицина
- ID:6000770
Где купить (1)
Цена от 14442 р. до 14442 р. в 1 магазинах
Магазин | Цена | Наличие |
---|---|---|
Описание
Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development. • Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability • Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development • Explains how preclinical animal models – used in preclinical testing – and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development • Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS) • Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development
Смотри также о книге.
О книге
Параметр | Значение |
---|---|
Автор(ы) | Ayman F. El-Kattan |
Издатель | John Wiley & Sons Limited |
ISBN | 978-1-118-91694-0 |
Отзывы (0)
Добавить отзыв
Книги: Фармакология - издательство "John Wiley & Sons Limited"
Категория 11553 р. - 17330 р.